Introduction to the Collins Laboratory
Historically, females have been understudied in the context of preclinical and clinical trials contributing to an overall reduced knowledge of basic female cardiovascular biology and also how the female heart responds to physiological and pathological stress. Therefore, the overall mission of the Collins lab is to understand the mechanisms contributing to female cardiovascular health and resilience.
Under this larger thematic focus, the Collins lab has several areas of active investigation, they include:
Pathophysiological and etiological mechanisms of peripartum cardiomyopathy and other pregnancy-associated cardiovascular complications.
The response of the female heart to pathological stressors and mechanisms underlying sex-dependent changes in post-infarction remodeling.
Emily B Schulman-Geltzer, Helen E Collins, Bradford G Hill, Kyle L Fulghum
Curr Heart Fail Rep., 2023
Helen E. Collins
Redox Biology, 2023
Xiaosen Ouyang, Sayan Bakshi, Gloria A. Benavides, Zhihuan Sun, Gerardo Hernandez-Moreno, Helen E. Collins, Mariame S. Kane, Silvio Litovsky, Martin E. Young, John C. Chatham, Victor Darley-Usmar, Adam R. Wende, Jianhua Zhang.
Physiological Reports, vol. 11(9), 2023, pp. e15686
Helen E. Collins, Dingguo Zhang, John C. Chatham
Frontiers in Aging, 2022
Helen E Collins, Joshua C. Anderson, Adam R. Wende, John C. Chatham
Physiological reports, 2022
Helen E Collins, PhD, FAHA
Assistant Professor of Medicine
Delia Baxter Building, Room 321C, University of Louisville, 580 South Preston Street, Louisville, KY